CREBL2 Polyclonal / Unconjugated /

Product Details
Supplier Proteintech
Catalog #: 18007-1-AP-20UL (View supplier product page)
Size 20 μl
Price $149.00
Antigen CREBL2
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications WB, ELISA
Description The CREBL2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CREBL2. This antibody recognizes human, mouse, rat antigen. The CREBL2 antibody has been validated for the following applications: WB, ELISA analysis.
About CREBL2 and Purified
CREBL2 cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra