Bcl-10 Polyclonal / Unconjugated /

Product Details
Supplier Proteintech
Catalog #: 17732-1-AP-150UL (View supplier product page)
Size 150 μl
Price $449.00
Antigen Bcl-10
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications WB, IHC, ICC/IF, ELISA
Description The BCL10 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human BCL10. This antibody recognizes human, mouse, rat antigen. The BCL10 antibody has been validated for the following applications: WB, IHC, IF/ICC, ELISA analysis.
About Bcl-10 and Purified
Bcl-10 This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Purified Excitation and Emission Spectra