Glutamate Dehydrogenase Polyclonal / Unconjugated /

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Product Details
Supplier Proteintech
Catalog #: 14299-1-AP-20UL (View supplier product page)
Size 20 μl
Price $149.00
Antigen Glutamate Dehydrogenase
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications WB, IHC, IF, IP, CoIP, ELISA
Description The GLUD1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GLUD1. This antibody recognizes human, mouse, rat antigen. The GLUD1 antibody has been validated for the following applications: WB, IP, IHC, ELISA analysis.
About Glutamate Dehydrogenase and Purified
Glutamate Dehydrogenase This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016]
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