GAD1 Polyclonal / Unconjugated /

Citations: (26)
Product Details
Supplier Proteintech
Catalog #: 10408-1-AP-20UL (View supplier product page)
Size 20 μl
Price $149.00
Antigen GAD1
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications WB, IHC, IF, IP, ELISA
Description The GAD1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GAD1. This antibody recognizes human, mouse, rat antigen. The GAD1 antibody has been validated for the following applications: WB, IHC, IF-Fro, IP, ELISA analysis.
About GAD1 and Purified
GAD1 This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
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