ANTXR1 / Janelia Fluor 585 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-21501JF585 (View supplier product page)
Size 100 μl
Price $499.00
Antigen ANTXR1
Clone
Host Rabbit
Isotype IgG
Conjugate Janelia Fluor 585
Target Species Human, Mouse, Rat
Applications ELISA, WB, ICC, IF
Description TEM8/ANTXR1 Antibody [Janelia Fluor® 585]
About ANTXR1 and Janelia Fluor 585
ANTXR1 This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
Janelia Fluor 585 Janelia Fluor® 585 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 585 has an excitation peak at 585 nm and an emission peak at 609 nm.
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Janelia Fluor 585 Excitation and Emission Spectra