Sclerostin / DyLight 350 / setrusumab

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28655UV (View supplier product page)
Size 100 μl
Price $379.00
Antigen Sclerostin
Clone setrusumab
Host Human
Isotype IgG2
Conjugate DyLight 350
Target Species Human
Applications FC, ELISA, Functional
Description SOST/Sclerostin Antibody (setrusumab) [DyLight 350]
About Sclerostin and DyLight 350
Sclerostin Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

DyLight 350 Excitation and Emission Spectra