Siglec-8 / Biotin / lirentelimab

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28171B (View supplier product page)
Size 100 μl
Price $379.00
Antigen Siglec-8
Clone lirentelimab
Host Human
Isotype IgG1
Conjugate Biotin
Target Species Human
Applications FC, ELISA, Functional
Description Siglec-8 Antibody (lirentelimab) [Biotin]
About Siglec-8 and Biotin
Siglec-8 Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010]
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Biotin Excitation and Emission Spectra