PSMA / HRP / rosopatamab

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28155H (View supplier product page)
Size 100 μl
Price $379.00
Antigen PSMA
Clone rosopatamab
Host Human
Isotype IgG1
Conjugate HRP
Target Species Human
Applications FC, ELISA, Functional
Description PSMA/FOLH1/NAALADase I Antibody (rosopatamab) [HRP]
About PSMA and HRP
PSMA This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010]
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HRP Excitation and Emission Spectra