PD-1 / DyLight 594 / spartalizumab
PD-1 / DyLight 594 / spartalizumab
Product Details
Supplier | Novus Biologicals, a Bio-Techne brand | |
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Catalog #: | NBP3-28111DL594 (View supplier product page) | |
Size | 100 μl | |
Price | $379.00 | |
Antigen | PD-1 | |
Clone | spartalizumab | |
Host | Human | |
Isotype | IgG4 | |
Conjugate | DyLight 594 | |
Target Species | Human | |
Applications | FC, ELISA, Functional | |
Description | PD-1 Antibody (spartalizumab) [DyLight 594] |
About PD-1 and DyLight 594
PD-1 | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020] | |
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DyLight 594 | DyLight™ 594 has an excitation peak at 593 nm and an emission peak at 618 nm and is spectrally similar to Alexa Fluor™ 594 and Texas Red. DyLight™ 594 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
Reviews & Ratings
DyLight 594 Excitation and Emission Spectra
$379.00
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