PD-1 / Alexa Fluor 532 / UCB patent anti-PD-1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28259AF532 (View supplier product page)
Size 100 μl
Price $379.00
Antigen PD-1
Clone UCB patent anti-PD-1
Host Human
Isotype IgG4
Conjugate Alexa Fluor 532
Target Species Human
Applications FC, ELISA, Functional
Description PD-1 Antibody (UCB patent anti-PD-1) [Alexa Fluor® 532]
About PD-1 and Alexa Fluor 532
PD-1 Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
Alexa Fluor 532 Alexa Fluor™ 532 (AF532, Alexa 532) has an excitation peak at 532 nm and an emission peak at 554 nm, and is spectrally similar to Cy®3 (GE Healthcare), TRITC, iFluor® 514 (ATT Bioquest) and iFluor® 546 (ATT Bioquest). Many flow cytometers are equipped with 532nm lasers, so while Alexa 532 can be used for flow cytometry, PE is more commonly used due to its brightness and spectral characteristics. This dye is commonly used for fluorescence microscopy applications.
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Alexa Fluor 532 Excitation and Emission Spectra