PD-1 / Alexa Fluor 350 / pembrolizumab

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28113AF350 (View supplier product page)
Size 100 μl
Price $379.00
Antigen PD-1
Clone pembrolizumab
Host Human
Isotype IgG4
Conjugate Alexa Fluor 350
Target Species Human
Applications FC, ELISA, Functional
Description PD-1 Antibody (pembrolizumab) [Alexa Fluor® 350]
About PD-1 and Alexa Fluor 350
PD-1 Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra