PAR2 / Alexa Fluor 647 / Amgen patent anti-PAR-2

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28881AF647 (View supplier product page)
Size 100 μl
Price $379.00
Antigen PAR2
Clone Amgen patent anti-PAR-2
Host Human
Isotype IgG2
Conjugate Alexa Fluor 647
Target Species Human
Applications FC, ELISA, Functional
Description PAR2 Antibody (Amgen patent anti-PAR-2) [Alexa Fluor® 647]
About PAR2 and Alexa Fluor 647
PAR2 This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity. [provided by RefSeq, Jun 2016]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra