Osteoactivin / DyLight 550 / glembatumumab

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28144R (View supplier product page)
Size 100 μl
Price $379.00
Antigen Osteoactivin
Clone glembatumumab
Host Human
Isotype IgG2
Conjugate DyLight 550
Target Species Human
Applications FC, ELISA, Functional
Description Osteoactivin/GPNMB Antibody (glembatumumab) [DyLight 550]
About Osteoactivin and DyLight 550
Osteoactivin The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
DyLight 550 DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 550 Excitation and Emission Spectra