Mineralocorticoid Receptor / DyLight 650 / PCRP-NR3C2-1E3

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-26967C (View supplier product page)
Size 100 μl
Price $599.00
Antigen Mineralocorticoid Receptor
Clone PCRP-NR3C2-1E3
Host Mouse
Isotype IgG1
Conjugate DyLight 650
Target Species Human
Applications FC
Description Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3) [DyLight 650]
About Mineralocorticoid Receptor and DyLight 650
Mineralocorticoid Receptor This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
DyLight 650 DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 650 Excitation and Emission Spectra