Mineralocorticoid Receptor / DyLight 350 / PCRP-NR3C2-1E3

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-26967UV (View supplier product page)
Size 100 μl
Price $599.00
Antigen Mineralocorticoid Receptor
Clone PCRP-NR3C2-1E3
Host Mouse
Isotype IgG1
Conjugate DyLight 350
Target Species Human
Applications FC
Description Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3) [DyLight 350]
About Mineralocorticoid Receptor and DyLight 350
Mineralocorticoid Receptor This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra