Mineralocorticoid Receptor / Alexa Fluor 750 / PCRP-NR3C2-1E3

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-26967AF750 (View supplier product page)
Size 100 μl
Price $599.00
Antigen Mineralocorticoid Receptor
Clone PCRP-NR3C2-1E3
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 750
Target Species Human
Applications FC
Description Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3) [Alexa Fluor® 750]
About Mineralocorticoid Receptor and Alexa Fluor 750
Mineralocorticoid Receptor This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Alexa Fluor 750 Alexa Fluor™ 750 (AF750, Alexa 750) has an excitation peak at 749 nm and an emission peak at 775 nm, and is spetrally similar to Cy®7 (GE Healthcare), APC-Fire™ 750 (BioLegend), CF®®750 (Biotium), DyLight™ 750 (ThermoFisher Scientific), iFluor® 750 (ATT Bioquest) and iFluor® 790 (ATT Bioquest). Alexa 750 is often used as a tandem fluorophore in flow cytometry or used on its own in fluorescence microscopy, in-vivo fluorescence microscopy or super-resolution microscopy applications.
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Alexa Fluor 750 Excitation and Emission Spectra