Mesothelin / DyLight 488 / amatuximab

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28069G (View supplier product page)
Size 100 μl
Price $379.00
Antigen Mesothelin
Clone amatuximab
Host Human
Isotype IgG1
Conjugate DyLight 488
Target Species Human
Applications FC, ELISA, Functional
Description Mesothelin Antibody (amatuximab) [DyLight 488]
About Mesothelin and DyLight 488
Mesothelin This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra