Mesothelin / DyLight 405 / amatuximab

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28069V (View supplier product page)
Size 100 μl
Price $379.00
Antigen Mesothelin
Clone amatuximab
Host Human
Isotype IgG1
Conjugate DyLight 405
Target Species Human
Applications FC, ELISA, Functional
Description Mesothelin Antibody (amatuximab) [DyLight 405]
About Mesothelin and DyLight 405
Mesothelin This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra