Integrin beta 7 / DyLight 350 / Genentech patent anti-Integrin beta7

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28000UV (View supplier product page)
Size 100 μl
Price $379.00
Antigen Integrin beta 7
Clone Genentech patent anti-Integrin beta7
Host Human
Isotype IgG1
Conjugate DyLight 350
Target Species Human
Applications FC, ELISA, Functional
Description Integrin beta 7 Antibody (Genentech patent anti-Integrin beta7) [DyLight 350]
About Integrin beta 7 and DyLight 350
Integrin beta 7 This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra