CD51 / DyLight 350 / abituzumab

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28527UV (View supplier product page)
Size 100 μl
Price $379.00
Antigen CD51
Clone abituzumab
Host Human
Isotype IgG2
Conjugate DyLight 350
Target Species Human
Applications FC, ELISA, Functional
Description Integrin alpha V/CD51 Antibody (abituzumab) [DyLight 350]
About CD51 and DyLight 350
CD51 The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra