CD11a / Janelia Fluor 669 / DF1524

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-11533JF669 (View supplier product page)
Size 100 μl
Price $619.00
Antigen CD11a
Clone DF1524
Host Mouse
Isotype IgG2b κ
Conjugate Janelia Fluor 669
Target Species Human
Applications FC, IF, ICC
Description Integrin alpha L/CD11a Antibody (DF1524) [Janelia Fluor® 669]
About CD11a and Janelia Fluor 669
CD11a ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Janelia Fluor 669 Janelia Fluor® 669 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 669 has an excitation peak at 669 nm and an emission peak at 682 nm.
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Janelia Fluor 669 Excitation and Emission Spectra