IL-6 / Janelia Fluor 525 / Chugai SK2

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28422JF525 (View supplier product page)
Size 100 μl
Price $379.00
Antigen IL-6
Clone Chugai SK2
Host Human
Isotype IgG1
Conjugate Janelia Fluor 525
Target Species Human
Applications FC, ELISA, Functional
Description IL-6 Antibody (Chugai SK2) [Janelia Fluor® 525]
About IL-6 and Janelia Fluor 525
IL-6 This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020]
Janelia Fluor 525 Janelia Fluor® 525 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 525 has an excitation peak at 525 nm and an emission peak at 549 nm.
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Janelia Fluor 525 Excitation and Emission Spectra