IL-6 / Alexa Fluor 405 / ziltivekimab

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28449AF405 (View supplier product page)
Size 100 μl
Price $379.00
Antigen IL-6
Clone ziltivekimab
Host Human
Isotype IgG1
Conjugate Alexa Fluor 405
Target Species Human
Applications FC, ELISA, Functional
Description IL-6 Antibody (ziltivekimab) [Alexa Fluor® 405]
About IL-6 and Alexa Fluor 405
IL-6 This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra