CD125 / DyLight 488 / benralizumab

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28011G (View supplier product page)
Size 100 μl
Price $379.00
Antigen CD125
Clone benralizumab
Host Human
Isotype IgG1
Conjugate DyLight 488
Target Species Human
Applications FC, ELISA, Functional
Description IL-5R alpha/CD125 Antibody (benralizumab) [DyLight 488]
About CD125 and DyLight 488
CD125 The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra