IL-23 / Alexa Fluor 647 / guselkumab

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28334AF647 (View supplier product page)
Size 100 μl
Price $379.00
Antigen IL-23
Clone guselkumab
Host Human
Isotype IgG1
Conjugate Alexa Fluor 647
Target Species Human
Applications FC, ELISA, Functional
Description IL-23 Antibody (guselkumab) [Alexa Fluor® 647]
About IL-23 and Alexa Fluor 647
IL-23 This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. [provided by RefSeq, Jul 2008]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra