IL-18 / DyLight 550 / GSK 1070806

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-27989R (View supplier product page)
Size 100 μl
Price $379.00
Antigen IL-18
Clone GSK 1070806
Host Human
Isotype IgG1
Conjugate DyLight 550
Target Species Human
Applications FC, ELISA, Functional
Description IL-18/IL-1F4 Antibody (GSK 1070806) [DyLight 550]
About IL-18 and DyLight 550
IL-18 The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020]
DyLight 550 DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 550 Excitation and Emission Spectra