IL-18 / Alexa Fluor 594 / GSK 1070806

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-27989AF594 (View supplier product page)
Size 100 μl
Price $379.00
Antigen IL-18
Clone GSK 1070806
Host Human
Isotype IgG1
Conjugate Alexa Fluor 594
Target Species Human
Applications FC, ELISA, Functional
Description IL-18/IL-1F4 Antibody (GSK 1070806) [Alexa Fluor® 594]
About IL-18 and Alexa Fluor 594
IL-18 The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020]
Alexa Fluor 594 Alexa Fluor™ 594 (AF594, Alexa 594) has an excitation peak at 590 nm and an emission peak at 617 nm, and is spectrally similar to Texas Red (ThermoFisher Scientific), DyLight™ 594 (ThermoFisher Scientific), iFluor® 594 (ATT Bioquest) and iFluor® 610 (ATT Bioquest), CF®594 (Biotium), and ATTO 594 (ATTO-TEC). Alexa 594 is commonly used for flow cytometry,fluorescence microscopy and super-resolution microscopy. It is very bright, photostable, and pH insensitive.
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Alexa Fluor 594 Excitation and Emission Spectra