IL-18 / Alexa Fluor 488 / GSK 1070806

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-27989AF488 (View supplier product page)
Size 100 μl
Price $379.00
Antigen IL-18
Clone GSK 1070806
Host Human
Isotype IgG1
Conjugate Alexa Fluor 488
Target Species Human
Applications FC, ELISA, Functional
Description IL-18/IL-1F4 Antibody (GSK 1070806) [Alexa Fluor® 488]
About IL-18 and Alexa Fluor 488
IL-18 The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Alexa Fluor 488 Excitation and Emission Spectra