IL-18 / Alexa Fluor 350 / ABT-325

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28597AF350 (View supplier product page)
Size 100 μl
Price $379.00
Antigen IL-18
Clone ABT-325
Host Human
Isotype IgG1
Conjugate Alexa Fluor 350
Target Species Human
Applications FC, ELISA, Functional
Description IL-18/IL-1F4 Antibody (ABT-325) [Alexa Fluor® 350]
About IL-18 and Alexa Fluor 350
IL-18 The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra