IL-13 / DyLight 405 / dectrekumab

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28003V (View supplier product page)
Size 100 μl
Price $379.00
Antigen IL-13
Clone dectrekumab
Host Human
Isotype IgG1
Conjugate DyLight 405
Target Species Human
Applications FC, ELISA, Functional
Description IL-13 Antibody (dectrekumab) [DyLight 405]
About IL-13 and DyLight 405
IL-13 This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra