HP1 alpha / Janelia Fluor 585 / RAB-C133

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-20127JF585 (View supplier product page)
Size 100 μl
Price $409.00
Antigen HP1 alpha
Clone RAB-C133
Host Rabbit
Isotype IgG κ
Conjugate Janelia Fluor 585
Target Species Human
Applications FC, ELISA, IP, WB, Mass Spectrometry, ChIP, ICC, IF
Description HP1 alpha Antibody (RAB-C133) [Janelia Fluor® 585]
About HP1 alpha and Janelia Fluor 585
HP1 alpha This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Janelia Fluor 585 Janelia Fluor® 585 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 585 has an excitation peak at 585 nm and an emission peak at 609 nm.
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Janelia Fluor 585 Excitation and Emission Spectra