c-Met / Alexa Fluor 700 / SAIT301

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-27954AF700 (View supplier product page)
Size 100 μl
Price $379.00
Antigen c-Met
Clone SAIT301
Host Human
Isotype IgG1
Conjugate Alexa Fluor 700
Target Species Human
Applications FC, ELISA, Functional
Description HGFR/c-MET Antibody (SAIT301) [Alexa Fluor® 700]
About c-Met and Alexa Fluor 700
c-Met This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Alexa Fluor 700 Excitation and Emission Spectra