c-Met / Alexa Fluor 594 / Korea RIBB patent anti-cMet

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28291AF594 (View supplier product page)
Size 100 μl
Price $379.00
Antigen c-Met
Clone Korea RIBB patent anti-cMet
Host Human
Isotype IgG1
Conjugate Alexa Fluor 594
Target Species Human
Applications FC, ELISA, Functional
Description HGFR/c-MET Antibody (Korea RIBB patent anti-cMet) [Alexa Fluor® 594]
About c-Met and Alexa Fluor 594
c-Met This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016]
Alexa Fluor 594 Alexa Fluor™ 594 (AF594, Alexa 594) has an excitation peak at 590 nm and an emission peak at 617 nm, and is spectrally similar to Texas Red (ThermoFisher Scientific), DyLight™ 594 (ThermoFisher Scientific), iFluor® 594 (ATT Bioquest) and iFluor® 610 (ATT Bioquest), CF®594 (Biotium), and ATTO 594 (ATTO-TEC). Alexa 594 is commonly used for flow cytometry,fluorescence microscopy and super-resolution microscopy. It is very bright, photostable, and pH insensitive.
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Alexa Fluor 594 Excitation and Emission Spectra