Alkaline Phosphatase Monoclonal / Unconjugated / VIAP1

Citations: (2)
Product Details
Supplier Thermo Fisher Scientific
Catalog #: ME6200 (View supplier product page)
Size 500 μl
Price $236.00
Antigen Alkaline Phosphatase
Clone VIAP1
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Bacteria
Applications FC
Description ALPL Monoclonal Antibody (VIAP1)
About Alkaline Phosphatase and Purified
Alkaline Phosphatase This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015]
Citations
PMID 17071759
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Purified Excitation and Emission Spectra