CD357 / PE / Korea Natl.Cancer Ctr. patent anti-GITR

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28151PE (View supplier product page)
Size 100 μl
Price $379.00
Antigen CD357
Clone Korea Natl.Cancer Ctr. patent anti-GITR
Host Human
Isotype IgG1
Conjugate PE
Target Species Human
Applications FC, ELISA, Functional
Description GITR/TNFRSF18 Antibody (Korea Natl.Cancer Ctr. patent anti-GITR) [PE]
About CD357 and PE
CD357 This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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PE Excitation and Emission Spectra