CD357 / Janelia Fluor 646 / Korea Natl.Cancer Ctr. patent anti-GITR

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28151JF646 (View supplier product page)
Size 100 μl
Price $379.00
Antigen CD357
Clone Korea Natl.Cancer Ctr. patent anti-GITR
Host Human
Isotype IgG1
Conjugate Janelia Fluor 646
Target Species Human
Applications FC, ELISA, Functional
Description GITR/TNFRSF18 Antibody (Korea Natl.Cancer Ctr. patent anti-GITR) [Janelia Fluor® 646]
About CD357 and Janelia Fluor 646
CD357 This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
Janelia Fluor 646 Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.
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Janelia Fluor 646 Excitation and Emission Spectra