GDF-15 / Alexa Fluor 532 / ponsegromab

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28880AF532 (View supplier product page)
Size 100 μl
Price $379.00
Antigen GDF-15
Clone ponsegromab
Host Human
Isotype IgG1
Conjugate Alexa Fluor 532
Target Species Human
Applications FC, ELISA, Functional
Description GDF-15 Antibody (ponsegromab) [Alexa Fluor® 532]
About GDF-15 and Alexa Fluor 532
GDF-15 This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. [provided by RefSeq, Aug 2016]
Alexa Fluor 532 Alexa Fluor™ 532 (AF532, Alexa 532) has an excitation peak at 532 nm and an emission peak at 554 nm, and is spectrally similar to Cy®3 (GE Healthcare), TRITC, iFluor® 514 (ATT Bioquest) and iFluor® 546 (ATT Bioquest). Many flow cytometers are equipped with 532nm lasers, so while Alexa 532 can be used for flow cytometry, PE is more commonly used due to its brightness and spectral characteristics. This dye is commonly used for fluorescence microscopy applications.
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Alexa Fluor 532 Excitation and Emission Spectra