GAD65 / DyLight 488 / U.Washington patent anti-GAD65

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28688G (View supplier product page)
Size 100 μl
Price $379.00
Antigen GAD65
Clone U.Washington patent anti-GAD65
Host Human
Isotype IgG1
Conjugate DyLight 488
Target Species Human
Applications FC, ELISA, Functional
Description GAD2/GAD65 Antibody (U.Washington patent anti-GAD65) [DyLight 488]
About GAD65 and DyLight 488
GAD65 This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra