Erythropoietin R / DyLight 488 / Abbott patent anti-EPO Receptor

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28535G (View supplier product page)
Size 100 μl
Price $379.00
Antigen Erythropoietin R
Clone Abbott patent anti-EPO Receptor
Host Human
Isotype IgG2
Conjugate DyLight 488
Target Species Human
Applications FC, ELISA, Functional
Description Erythropoietin R Antibody (Abbott patent anti-EPO Receptor) [DyLight 488]
About Erythropoietin R and DyLight 488
Erythropoietin R This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra