EphB2 / Alexa Fluor 647 / Genentech patent anti-EphB2

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28529AF647 (View supplier product page)
Size 100 μl
Price $379.00
Antigen EphB2
Clone Genentech patent anti-EphB2
Host Human
Isotype IgG1
Conjugate Alexa Fluor 647
Target Species Human
Applications FC, ELISA, Functional
Description EphB2 Antibody (Genentech patent anti-EphB2) [Alexa Fluor® 647]
About EphB2 and Alexa Fluor 647
EphB2 This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra