EGF Receptor / Janelia Fluor 646 / tomuzotuximab

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28613JF646 (View supplier product page)
Size 100 μl
Price $379.00
Antigen EGF Receptor
Clone tomuzotuximab
Host Human
Isotype IgG1
Conjugate Janelia Fluor 646
Target Species Human
Applications FC, ELISA, Functional
Description EGFR Antibody (tomuzotuximab) [Janelia Fluor® 646]
About EGF Receptor and Janelia Fluor 646
EGF Receptor The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020]
Janelia Fluor 646 Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.
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Janelia Fluor 646 Excitation and Emission Spectra