Dnmt3b / Unconjugated / SR2574

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-27699-100ul (View supplier product page)
Size 100 μl
Price $339.00
Antigen Dnmt3b
Clone SR2574
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications WB, ICC, IF
Description DNMT3B Antibody (SR2574)
About Dnmt3b and Purified
Dnmt3b CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011]
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Purified Excitation and Emission Spectra