Estrogen Sulfotransferase / FITC / SULT1E1/7124

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-27015F (View supplier product page)
Size 100 μl
Price $599.00
Antigen Estrogen Sulfotransferase
Clone SULT1E1/7124
Host Mouse
Isotype IgG2 κ
Conjugate FITC
Target Species Human
Applications WB, IHC-P
Description Cytosolic Sulfotransferase 1E1/SULT1E1 Antibody (SULT1E1/7124) [FITC]
About Estrogen Sulfotransferase and FITC
Estrogen Sulfotransferase Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors. [provided by RefSeq, Jul 2008]
FITC Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark.
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FITC Excitation and Emission Spectra