Complement Factor B / DyLight 755 / Genentech patent anti-Factor B

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28833IR (View supplier product page)
Size 100 μl
Price $379.00
Antigen Complement Factor B
Clone Genentech patent anti-Factor B
Host Human
Isotype IgG1
Conjugate DyLight 755
Target Species Human
Applications FC, ELISA, Functional
Description Complement Factor B Antibody (Genentech patent anti-Factor B) [DyLight 755]
About Complement Factor B and DyLight 755
Complement Factor B This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq, Jul 2008]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra