Complement C2 / Alexa Fluor 647 / ARGX-117

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28215AF647 (View supplier product page)
Size 100 μl
Price $379.00
Antigen Complement C2
Clone ARGX-117
Host Human
Isotype IgG1
Conjugate Alexa Fluor 647
Target Species Human
Applications FC, ELISA, Functional
Description Complement Component C2 Antibody (ARGX-117) [Alexa Fluor® 647]
About Complement C2 and Alexa Fluor 647
Complement C2 Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.[provided by RefSeq, Mar 2009]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra