Complement C5 / DyLight 755 / lendalizumab

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28576IR (View supplier product page)
Size 100 μl
Price $379.00
Antigen Complement C5
Clone lendalizumab
Host Human
Isotype IgG2
Conjugate DyLight 755
Target Species Human
Applications FC, ELISA, Functional
Description Complement C5 Antibody (lendalizumab) [DyLight 755]
About Complement C5 and DyLight 755
Complement C5 This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra