Claudin-6 / Alexa Fluor 700 / AE3-20

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28473AF700 (View supplier product page)
Size 100 μl
Price $379.00
Antigen Claudin-6
Clone AE3-20
Host Human
Isotype IgG
Conjugate Alexa Fluor 700
Target Species Human
Applications FC, ELISA, Functional
Description Claudin-6 Antibody (AE3-20) [Alexa Fluor® 700]
About Claudin-6 and Alexa Fluor 700
Claudin-6 Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra