Claudin-6 / Alexa Fluor 405 / IM-302

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28246AF405 (View supplier product page)
Size 100 μl
Price $379.00
Antigen Claudin-6
Clone IM-302
Host Human
Isotype IgG
Conjugate Alexa Fluor 405
Target Species Chicken
Applications FC, ELISA, Functional
Description Claudin-6 Antibody (IM-302) [Alexa Fluor® 405]
About Claudin-6 and Alexa Fluor 405
Claudin-6 Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
Citations
Additional
Sources
Reviews & Ratings
Alexa Fluor 405 Excitation and Emission Spectra