CD8b / Janelia Fluor 635 / 39

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-89751JF635 (View supplier product page)
Size 100 μl
Price $549.00
Antigen CD8b
Clone 39
Host Rabbit
Isotype IgG
Conjugate Janelia Fluor 635
Target Species Human
Applications IHC, IHC-P
Description CD8 beta Antibody (039) [Janelia Fluor® 635]
About CD8b and Janelia Fluor 635
CD8b The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
Janelia Fluor 635 Janelia Fluor® 635 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 635 has an excitation peak at 635 nm and an emission peak at 652 nm.
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Janelia Fluor 635 Excitation and Emission Spectra