CD59 / DyLight 550 / Quark patent anti-CD59

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-28046R (View supplier product page)
Size 100 μl
Price $379.00
Antigen CD59
Clone Quark patent anti-CD59
Host Human
Isotype IgG1
Conjugate DyLight 550
Target Species Human
Applications FC, ELISA, Functional
Description CD59 Antibody (Quark patent anti-CD59) [DyLight 550]
About CD59 and DyLight 550
CD59 This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
DyLight 550 DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 550 Excitation and Emission Spectra